SDS Vault Safety Data Sheet Reference

R-22 Refrigerant (HCFC-22)

CAS: 75-45-6 Category: Refrigerants ⚠ WARNING
Also known as: HCFC-22, Chlorodifluoromethane, Freon 22, Arcton 4

Quick Facts

CAS Number75-45-6
Signal WordWARNING
GHS Hazard Classescompressed gas
NFPA RatingHealth: 1 / Flammability: 0 / Reactivity: 0
Common NamesHCFC-22, Chlorodifluoromethane, Freon 22, Arcton 4
PubChem CID6372

Hazard Summary

⚠ WARNING: Ozone-depleting HCFC refrigerant. Production phased out under Montreal Protocol — only recycled R-22 may be used for service. EPA Section 608 certification required. Simple asphyxiant in enclosed spaces.

GHS Hazard Pictograms

🔵 Compressed Gas

Hazard Statements (H-codes)

H280 – Contains gas under pressure; may explode if heated
H420 – Harms public health and environment (ozone-depleting substance)

Precautionary Statements (P-codes)

P410+P403 – Protect from sunlight; store in well-ventilated place
P260 – Do not breathe gas

First Aid Measures (Section 4)

👁 Eye Contact
Cryogenic contact: flush with tepid water. Seek medical attention.
🖐 Skin Contact
Cryogenic frostbite: rewarm with tepid water. Do not rub. Seek medical attention.
🫁 Inhalation
Remove to fresh air. Call 911 if unconscious.
🫦 Ingestion
Not applicable.

Storage & Handling

🔒 Storage & Handling: Upright in cool, well-ventilated area. Maximum 52 °C. EPA prohibits intentional venting.

PPE Requirements

Safety glasses
Cryogenic gloves for liquid handling
EPA 608 certification required
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