⚠ WARNING: High-pressure HFC refrigerant blend used in HVAC systems. Operates at 70% higher pressure than R-22 — requires R-410A rated equipment. Simple asphyxiant. EPA is phasing out under AIM Act; successor R-32 / R-454B being adopted.
GHS Hazard Pictograms
🔵 Compressed Gas
Hazard Statements (H-codes)
H280 – Contains gas under pressure; may explode if heated
H420 – Harms public health and environment (GWP 2088)
Precautionary Statements (P-codes)
P410+P403 – Protect from sunlight; store in well-ventilated place
P260 – Do not breathe gas
P271 – Use only in well-ventilated area
First Aid Measures (Section 4)
👁Eye Contact▼
Cryogenic liquid contact: flush with tepid water. Seek medical attention.
🖐Skin Contact▼
Frostbite from cryogenic contact. Rewarm with tepid water. Seek medical attention.
🫁Inhalation▼
Remove to fresh air. Call 911 if unconscious. Seek medical attention for any significant exposure.
🫦Ingestion▼
Not applicable.
Storage & Handling
🔒 Storage & Handling: Store upright in cool, well-ventilated area. Maximum 52 °C (125 °F). Use only R-410A rated cylinders and equipment.
PPE Requirements
Safety glasses
Cryogenic gloves for liquid handling
EPA Section 608 certification required for handling
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